Teenager, Stella Grant is hospitalized with cystic fibrosis. To ensure safety, she needs to be physically distanced by 6 feet from others. The one thing keeping Stella far from safety is Will Newman, who could care less about his diagnosis. An attraction between the two starts. As that continues, the worrisome of if Will's careless actions will influence Stella to lead herself towards harm.

Living in an unexpected reality, eighteen year old, Maddy Whitman, has never gone outside. She is allergic to the world. Has never once experienced anywhere other than the walls of her home that are separating her and the world. Until she meets the boy next door, Olly. Maddy has never experienced anything she feels for Olly before. They fall for each other, but the only thing keeping them apart is Maddy's illness. Both are determined to find a way to reach each other.

As teen who has never experienced romance, she writes her feelings through envelopes of love letters to her crushes. All five letters are kept in a green heart shaped box her mother left her before she passed. Those letters hold all of Lara Jean's emotion and feeling for each boy she had ever liked. Being super personal, no one knows about the letters, until they are received by each of the five boys.

After being diagnosed with lung cancer, Hazel Grace Lancaster decides to join a cancer kids supports group. There, she meets a boy by the name of Augustus Waters. After meeting each other, their bond amongst each other is rich and tight. Until, they both go on a loving trip and Augustus drops some devastating news that changes everything.

When two worlds, literally collide. Theodore Finch and Violet Markey. One who is interested in death while one is focused on their bright future. Though two people can be so different, the two manage to get along and help each other. Throughout their friendship, Violet proceeds to thrive while Theodore starts to sink further and further down.

Finding himself in a boarding school environment, Quentin Jacobsen adjusts in with his new friend group, he spots a girl. The girl by the name of Margo Roth Spiegalman, the one Q is so interested and on a look out for. After hanging out together for a bit, there seems to be an unknown mystery of Margo.